发明名称 ISOFLAVANE DERIVATIVES AND IMMUNOPOTENTIATING COMPOSITIONS CONTAINING THE SAME
摘要 An objective of the present invention is to provide a specific compound and composition for the prevention or therapy of diseases associated with immunodeficiency. Isoflavan derivatives which are a glycyrrhiza extract and chemical derivatives thereof, i.e., a compound represented by general formula (II): <CHEM> Äwhere R<1>, R<2>, R<3>, and R<4> may be identical with or different from one another and may each be hydrogen, an alkyl group which may be substituted, an alkenyl group which may be substituted, an alkynyl group which may be substituted, an acyl group which may be substituted, an aralkyl group which may be substituted, or a tri-substituted silyl group; G<1>, G<2>, and G<3> may be identical with or different from one another and may each be a hydrogen, an acyl group which may be substituted, or an aliphatic hydrocarbon group which may be substituted; symbol (*) indicates the presence of an asymmetric carbon atom, meaning an R form, an S form, or a mixture thereofÜ, or a salt thereof, or a hydrate thereof has immunoactivating actions, and is expected to provide effects as a biophylaxis function promoter by way of lymphocyte function promoting actions and bone marrow function promoting actions.
申请公布号 EP1057825(A1) 申请公布日期 2000.12.06
申请号 EP19990901889 申请日期 1999.01.27
申请人 SHIONOGI & CO., LTD. 发明人 MASAKI, SHUNICHIRO;TOJYO, TAKEHIKO;TAKASHIMA, AKIRA;SEO, SHUJIRO
分类号 A23L1/30;A61K8/49;A61K31/35;A61Q19/00;C07D311/58 主分类号 A23L1/30
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