发明名称 |
Pharmaceutical compositions for controlled release of soluble receptors |
摘要 |
PCT No. PCT/US96/03121 Sec. 371 Date Oct. 9, 1997 Sec. 102(e) Date Oct. 9, 1997 PCT Filed Mar. 1, 1996 PCT Pub. No. WO96/26738 PCT Pub. Date Sep. 6, 1996A controlled release pharmaceutical composition includes a biocompatible polymeric material, preferably polyethylene-vinyl acetate or poly(lactic-glucolic acid), having incorporated therein a soluble receptor capable of binding to its ligand and thus affecting the ligand's function. The soluble receptor is preferably the soluble form of TNF alpha receptor. Such compositions are for use in the treatment of disorders in which neutralization of the deleterious effects of TNF alpha is required. |
申请公布号 |
IL112834(A) |
申请公布日期 |
2000.12.06 |
申请号 |
IL19950112834 |
申请日期 |
1995.03.01 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;BEN GURION UNIVERSITY OF THE NEGEV |
发明人 |
DAVID WALLACH;JOSEPH KOST;ROM ELIAZ |
分类号 |
A61K9/08;A61K9/00;A61K9/16;A61K38/00;A61K38/17;A61K38/21;A61K38/22;A61K45/00;A61K47/48;A61P25/00;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61P37/00;A61P43/00;C08L101/00 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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