| 发明名称 |
NOVEL ORGANIC ANION TRANSPORT PROTEINS |
| 摘要 |
The current invention discloses nucleic acid and amino acid sequences for novel organic anion transfer proteins ("OATPs"). The invention encompasses t he OATPs described herein, together with vectors containing the cDNA sequences, host cells containing the vectors and polypeptides having all or part of an OATP. Also encompasses are uses for OATPs for targeting drugs to specific organs and for modulating the concentration of endogenous substrates.</SDOAB >
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| 申请公布号 |
CA2374729(A1) |
申请公布日期 |
2000.11.30 |
| 申请号 |
CA20002374729 |
申请日期 |
2000.05.19 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
WU, YULI;ZHU, YINGJIE;WANG, ZHAOQING;LYNCH, JEAN S.;KIRCHGESSNER, TODD G.;YANG, WEN-PIN;HSIANG, BONNIE;HUANG, XIN |
| 分类号 |
G01N33/50;A61K47/48;C07K14/47;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;G01N33/15;(IPC1-7):C12N15/12;A61K38/16;A61K38/17;C07K14/435;G01N33/53;G01N33/567;C12N15/63;C12N15/64 |
主分类号 |
G01N33/50 |
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