NEW POLYPEPTIDES AND THEIR USE FOR THE RESCUE OF FUSION DEFECTIVE VIRUS OR RETROVIRUS GLYCOPROTEINS

摘要

The present invention relates to the use of at least one activating polypeptide comprising an amino acid sequence corresponding for instance to: the amino acid sequence of the surface subunit (SU) of an envelope glycoprotein of a first virus, or of a first retrovirus; for the rescue of the fusion property of a fusion defective envelope glycoprotein, which has the property of attachment to target cells and is inactive with respect to the fusion with said target cells, said fusion defective envelope glycoprotein belonging to a second virus or a second retrovirus of the same type as or of a different type from the above designated "first virus or first retrovirus".