发明名称 IONTOPHORESIS DEVICE FOR THE TRANSCUTANEOUS DELIVERY OF AN ACTIVE PRINCIPLE SUCH AS AN ANIONIC OLIGOSACCHARIDE
摘要 <p>PCT No. PCT/FR96/00114 Sec. 371 Date Sep. 29, 1997 Sec. 102(e) Date Sep. 29, 1997 PCT Filed Jan. 24, 1996 PCT Pub. No. WO96/22808 PCT Pub. Date Aug. 1, 1996A device comprising a reversible negative electrode in contact with a reservoir element containing an electrolyte which contains an active principle such as an anionic oligosaccharide, particularly a pentasaccharide, in at least partially ionised form, a positive electrode alone or in combination with an electrolyte-containing receptacle, and an electrical signal generator connectable to both electrodes. The generator is arranged to apply electrical signals between the electrodes, which signals have an average voltage such that the average current density generated between the electrodes is 0.05-0.25 mA/cm2. The amount of active principle in the reservoir element combined with the negative electrode is 0.5-12 mg per cm2. The amount of active principle in the reservoir element combined with the negative electrode is 0.5-12 mg per cm2 and per mAh of current through 1 cm2 of the electrode.</p>
申请公布号 GR3034097(T3) 申请公布日期 2000.11.30
申请号 GR20000401794T 申请日期 2000.08.02
申请人 SANOFI;ELF AQUITAINE;AKZO NOBEL N.V. 发明人 MULLER, DANIEL;BARBIER, ALAIN;SAUNAL, HENRY
分类号 A61N1/30;(IPC1-7):A61N1/30 主分类号 A61N1/30
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