发明名称 |
Mixture of fenofibrate and vitamin E and its therapeutic use |
摘要 |
<p>A combination of fenofibrate (FB) and a vitamin E deriv. (VE) comprises a co-micronisate of FB with a solid surfactant and a VE component comprising a tocopherol and/or its organic acid ester, provided that: (a) the co-micronisate comprises 33-200 mg FB and the amt. of VE is 100-600 IU; and (b) the ratio of FB in mg to VE in IU is 0.33-2 mg/IU. Also claimed is use of a combination of (FB) and(VE) for prepn. of a medicament for treating or preventing disorders associated with lipoprotein oxidn. notably atheromatous disorders, diabetes, essential arterial hypertension and restenosis, where FB is in the form of a co-micronisate with a solid surfactant.</p> |
申请公布号 |
GR3034147(T3) |
申请公布日期 |
2000.11.30 |
申请号 |
GR20000401842T |
申请日期 |
2000.08.08 |
申请人 |
LABORATOIRES FOURNIER S.A. |
发明人 |
EDGAR, ALAN DUNLAP;BELLAMY, FRANCOIS |
分类号 |
A61K9/16;A61K9/14;A61K31/235;A61K31/355;A61P3/06;A61P9/10;A61P43/00;(IPC1-7):A61K31/215 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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