| 摘要 |
Methods and system for general purpose analysis of images acquired from experimental data collected with automated feature-rich, high-throughput experimental data collection systems. A set of pre-determined general assay features is presented. An assay feature includes one or more measurements fo r an object in a digital photographic image acquired from the experimental dat a. The set of pre-determined general assay features includes object features, aggregate features and general purpose image processing features. A set of desired assay features is selected from the set of features. A set of images is processed using the desired assay features from the selected set of assay features. The methods and system help provide a general purpose assay development tool. The methods and system allow a biologist, other scientist or lab technician not trained in image processing techniques to quickly and easily design protocols and assays to analyze images acquired from experimental data (e.g., cells). The methods and system may improve the identification, selection, validation and screening of new drug compounds th at have been applied to populations of cells. The methods and system may also b e used to provide new bioinformatic techniques to manipulate experimental data including multiple digital photographic images. |
