发明名称 |
ISOFLAVONOID METHYLATION ENZYME |
摘要 |
Methods of genetically manipulating biologically active 4'-<i>O</i>-methylated isoflavonoids have been found based upon the regiospecifity of isoflavone 7-OMT in vivo. Upon transformation and expression of an isoflavonoid <i>O</i>-methyltransferase gene, up-regulation of IOMT in the transgenic plants can be used to increase the accumulation of 4'-<i>O</i>-methylated isoflavonoid phytolalexins, providing for increased disease resistance to the plant. Similar methods can be used to increase accumulation of 4'-<i>O</i>-methylated isoflavonoid nutraceuticals in plants. For down-regulation of IOMT in plants that naturally make 4'<i>O</i>-isoflavonoid phytoalexins and 4'-<i>O</i>-methylated isoflavonoid nutraceuticals, IOMT gene sequences can be transformed in the antisense orientation.
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申请公布号 |
WO0071736(A1) |
申请公布日期 |
2000.11.30 |
申请号 |
WO2000US13389 |
申请日期 |
2000.05.15 |
申请人 |
THE SAMUEL ROBERTS NOBLE FOUNDATION, INC.;DIXON, RICHARD, A.;HE, XIAN, Z. |
发明人 |
DIXON, RICHARD, A.;HE, XIAN, Z. |
分类号 |
A01H5/00;A23L1/30;A61K31/352;A61K36/48;A61P5/30;A61P7/00;A61P31/04;A61P35/00;A61P39/06;C12N5/10;C12N9/10;C12N15/09;C12N15/29;C12N15/82;C12P17/06;(IPC1-7):C12N15/82;C07K16/16 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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