| 摘要 |
The invention relates to a medicament for localised application which is to be used for hemostasis and/or sealing wounds and/or to promote the healing of wounds. The medicament has fibrinogen or fibrin, thrombin and one or more transglutaminases as active ingredients (which are produced conventionally from allogenic plasma or tissue, or are genetically engineered). As an additional active ingredient, the medicament contains one or more protease inhibitors, selected from the group of serpins which do not have any inhibiting effect on collagenases and elastases, whereby all active ingredients are of allogenic origin and are subjected to a method for depleting and/or for inactivating viruses, with the proviso that the inactivation of viruses in the protease inhibitor(s) is not carried out in t he presence of the other active ingredients.
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