发明名称 SUBSTITUTED IMIDAZOTHIAZOLES AS ANTIDEPRESSANT AGENTS
摘要 Compounds of Formula (I) including pharmaceutically acceptable salts thereof , in which A is S or O; R1 is H, halo, a C1-3 alkyl group or a C1-3 alkylthio group; R2 is H or fluoro; and R3 is methyl, ethyl or isopropyl are useful in the treatment of depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, obesity, drug addiction, drug abuse, cognitive disorders , Alzheimer's disease, cerebral ischaemia, obsessive-compulsive behaviour, pan ic attacks, social phobias, eating disorders such as bulimia, anorexia, snackin g and binge eating, non-insulin dependent diabetes mellitus, hyperglycaemia, hyperlipidaemia, stress and in the treatment and/or prophylaxis of seizures, neurological disorders such as epilepsy and/or conditions in which there is neurological damage such as stroke, brain trauma, cerebral ischaemia, head injuries and haemorrhage.
申请公布号 CA2374915(A1) 申请公布日期 2000.11.30
申请号 CA20002374915 申请日期 2000.05.11
申请人 KNOLL GMBH 发明人 BROUGH, PAUL ANDREW;HENSTOCK, VINCENT;WATTS, JOHN PAUL
分类号 A61K31/429;A61P1/04;A61P1/14;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P13/02;A61P15/10;A61P19/06;A61P25/02;A61P25/14;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P35/00;C07D513/04;(IPC1-7):C07D513/04;A61K31/425 主分类号 A61K31/429
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