| 摘要 |
<p>A method of determining which substance to administer to a vertebrate, a method of screening test substances, a method of determining the effect of a substance and a data-base for holding such information. A method is disclosed for obtaining information relating to which parameter of e.g. an osteoporotic bone is to be affected by a substance. A data-base is generated wherein substances, having an effect on bone, are identified together with information on which bone parameters are affected by the substance. By coordinating information in the database, a substance or a combination of substances is provided for providing the desire effect on the bone. It has been found that especially cortical porosity is affected by Bisphosphonates, and especially cortical thickness is affected by HRT.</p> |
