| 摘要 |
PROBLEM TO BE SOLVED: To provide an acetylcholine esterase(AChE) inhibitor which does not or scarcely generate a side effect and can inhibit or relax the crisis of Alzheimer's disease and the like. SOLUTION: This AChE inhibitor contains ajoene as an active ingredient. The ajoene inhibits the activity of the AChE having an action for inactivating the ACh which is a nervous transmitter substance. The inhibition of the activity of the AChE enables the inhibition or relaxation of diseases, such as Alzheimer's disease, which are considered to be caused by the excessive reduction or shortage of the ACh. The toxicity or side effects of the compound, E- or Z-ajoene, has not been reported, and the ajoene is considered to be harmless for human bodies. Thereby, the ajoene is liable not to cause a side effect, even when administered for a long period.
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