IMMUNOGENIC CONJUGATES COMPRISING A GROUP B MENINGOCOCCAL PORIN AND AN H. INFLUENZAE POLYSACCHARIDE

摘要

A substantially pure Haemophilus influenzae type b (Hib) polysaccharide with a refolded meningococcal outer membrane protein (rPorB) conjugate is new. Also claimed are: (a) a method for preparing an Hib polysaccharide-rRorB conjugate; (b) a Hib polysaccharide-rRorB conjugate obtained by the method of (a); (c) a pharmaceutical composition comprising the conjugate; and (d) a method for inducing an immune response to H. influenzae in an animal.