| 摘要 |
A self-calibrating adaptive-rate cardiac pacemaker having a measuring and processing device for measuring the course over time of a physiological variable over a predetermined portion of a heart cycle and for obtaining a course parameter from the course over time, a stimulation parameter determining device downstream of the measuring and processing device and controlled by a sequence controller for determining a stimulation parameter value, in particular the adaptive stimulation rate, a body sensor connected to one input of the stimulation parameter determining device, for detecting an exertion variable, whose signal is used jointly with the course parameter to determine the stimulation parameter value, and a stimulator unit for generating and outputting stimulation pulses at the determined stimulation parameter value. The measuring and processing device is arranged to obtain a plurality of different values of the course parameter as a function of at least one setting point in a calibration phase, and the stimulation parameter determining device has a stimulation parameter calculating device connected downstream of the measuring and processing device for calculating a plurality of stimulation parameter selection values, each as a function of one value for the course parameter, a reference parameter calculating device connected downstream of the body sensor, for calculating an activity -determined reference parameter value, a comparator unit connected on the input side to the stimulation parameter calculating device and to the reference parameter calculating device, for comparing the parameter selection values with the reference parameter value, and a decision-making device connected on the input side to the output of the comparator unit, for selecting one of the setting point values of the measuring and processing device, associated with the parameter selection values, as current setting point value for further control of the pacemaker, substantially on the basis of the course parameter as the outcome of the comparison.
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