| 发明名称 |
Therapeutic compositions and methods for treating disease states with myeloid progenitor inhibitory factor-1 (MPIF-1) |
| 摘要 |
Human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides (previously termed MIP-3 and chemokine beta 8 (CK beta 8 or ckb-8)) and fragments and mutants thereof are provided. The polypeptides may be used in a medicament for regulating hematopoiesis and lymphocyte trafficking, for facilitating wound healing, or for treating conditions such as myelopoietic dysfucntion, psorioasis, cancer, stroke, arthritis or other autoimmune diseases.
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| 申请公布号 |
NZ335003(A) |
申请公布日期 |
2000.11.24 |
| 申请号 |
NZ19970335003 |
申请日期 |
1997.09.30 |
| 申请人 |
HUMAN GENOME SCIENCES, INC |
发明人 |
GENTZ, REINER L;PATEL, VIKRAM;KREIDER, BRENT L;ZHANG, JUN;ANTONACCIO, MICHAEL;MENDRICK, DONNA;JIMENEZ, PABLO |
| 分类号 |
C12N15/09;A61K35/74;A61K35/76;A61K38/00;A61K48/00;A61P1/00;A61P7/00;A61P13/12;A61P17/02;A61P19/02;A61P29/00;A61P43/00;C07K14/52;C12N1/21;C12N5/10;C12N15/19;C12P21/02;(IPC1-7):C07K14/52;A61K38/19 |
主分类号 |
C12N15/09 |
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