发明名称 ION CHANNEL MODULATING AGENTS
摘要 The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general Formula (I) and a pharmaceutically acceptable salt or an oxide or a hydrate thereof, that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
申请公布号 WO0069823(A1) 申请公布日期 2000.11.23
申请号 WO2000DK00254 申请日期 2000.05.12
申请人 NEUROSEARCH A/S;JENSEN, BO, SKAANING;TEUBER, LENE;STROEBAEK, DORTE;CHRISTOPHERSEN, PALLE;OLESEN, SOEREN, PETER 发明人 JENSEN, BO, SKAANING;TEUBER, LENE;STROEBAEK, DORTE;CHRISTOPHERSEN, PALLE;OLESEN, SOEREN, PETER
分类号 C07D233/58;A61K31/05;A61K31/06;A61K31/13;A61K31/165;A61K31/167;A61K31/24;A61K31/40;A61K31/4164;A61K31/435;A61K31/4402;A61K31/4409;A61K31/4418;A61P1/00;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P11/06;A61P13/02;A61P13/12;A61P15/06;A61P15/08;A61P17/00;A61P17/14;A61P25/00;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/16;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/06;A61P43/00;C07C25/02;C07C205/06;C07C205/22;C07C233/07;C07C233/15;C07D207/32;C07D207/325;C07D213/04;C07D213/16;C07D213/30;C07D213/38;C07D213/53;C07D233/56;(IPC1-7):C07D213/04;A61K31/416 主分类号 C07D233/58
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