发明名称 |
MRI CONTRAST AGENT |
摘要 |
Provision of an MRI contrast agent wherein imaging capability is expressed only within the target abnormal cells, such as tumor, and imaging is not conducted at the site where imaging is not necessary, thereby to strikingly improve the detection sensitivity of the abnormal cells such as tumor. An MRI contrast agent, which comprises a complex of a polyanionic gadolinium (Gd) type contrast agent and a cationic polymer, or a complex of a polycationic Gd type contrast agent and an anionic polymer, both complexes being capable of forming a polyion complex, and which expresses an MRI capability at a neutral pH in the presence of a polymer electrolyte.
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申请公布号 |
WO0016811(A3) |
申请公布日期 |
2000.11.23 |
申请号 |
WO1999EP07090 |
申请日期 |
1999.09.16 |
申请人 |
SCHERING AKTIENGESELLSCHAFT;AKAIKE, TOSHIHIRO;MIWA, NAOTO;MIKAWA, MASAHITO;MARUYAMA, ATSUSHI |
发明人 |
AKAIKE, TOSHIHIRO;MIWA, NAOTO;MIKAWA, MASAHITO;MARUYAMA, ATSUSHI |
分类号 |
A61K49/00;A61K49/12;A61K49/18;(IPC1-7):A61K49/00 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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