发明名称 SUBSTITUTED 3-PYRIDYL-4-ARYLPYRROLES, AND RELATED THERAPEUTIC AND PROPHYLACTIC METHODS
摘要 This invention provides novel substituted 3-pyridyl-4-arylpyrroles, having chemical structure (I) and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by reducing TNF- alpha production and/or p38 activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.
申请公布号 WO0069847(A1) 申请公布日期 2000.11.23
申请号 WO2000US11531 申请日期 2000.04.28
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 BULLINGTON, JAMES
分类号 A61K31/4427;A61K31/4436;A61K31/4439;A61K31/4545;A61K31/506;A61K31/5377;A61P1/00;A61P1/02;A61P1/16;A61P1/18;A61P3/10;A61P7/00;A61P9/04;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/06;A61P17/14;A61P19/02;A61P19/10;A61P21/04;A61P25/00;A61P25/28;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D401/04;C07D401/14;C07D403/04;C07D409/14;C07D413/14;(IPC1-7):C07D401/04;A61K31/442 主分类号 A61K31/4427
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