G-PROTEIN COUPLED RECEPTOR (GPCR) BASED BIOSENSORS AND SENSE REPLICATION SYSTEMS

摘要

G-protein coupled receptor (GPCR) based sensors and sense replication systems are described. Methods for detecting and discriminating a stimulus corresponding to, or capable of mimicking and/or replacing a G-protein signal transduction system; and methods for mapping, transmitting and reproducing a selected stimulus at a remote location are described. The invention is useful in the electronic, telecommunications and entertainment industries, chemical (including contraband detection, food, flavors and fragrances) biological, medical and diagnostic techniques, as well as for drug discovery.