This invention relates to a novel series of compounds which are useful in the treatment or prevention of a physiological disorder associated with an excess of stimulation of the human Group I metabotropic glutamate receptors, especially those designated as mGluR5. This invention also provides methods for the treatment of such disorders, as well as pharmaceutical formulations which employ the novel metabotropic glutamate receptor antagonists to which the present invention relates.
申请公布号
WO0069816(A1)
申请公布日期
2000.11.23
申请号
WO2000US08223
申请日期
2000.05.17
申请人
ELI LILLY AND COMPANY;CLARK, BARRY, PETER;CWI, CYNTHIA, LYNN;HARRIS, JOHN, RICHARD;KINGSTON, ANN, ELIZABETH;SCOTT, WILLIAM, LEONARD
发明人
CLARK, BARRY, PETER;CWI, CYNTHIA, LYNN;HARRIS, JOHN, RICHARD;KINGSTON, ANN, ELIZABETH;SCOTT, WILLIAM, LEONARD
