CDX2 IS DOWNSTREAM MEDIATOR OF APC TUMOR SUPPRESSOR ACTIVITY
摘要
Human CDX2, a homeobox gene, has been identified as a downstream effector of tumor suppressor APC. APC induces the transcription of CDX2. This newly found relationship permits specific drug screening assays as well as therapeutic and diagnostic methods.
申请公布号
WO0070089(A1)
申请公布日期
2000.11.23
申请号
WO2000US12893
申请日期
2000.05.12
申请人
THE JOHNS HOPKINS UNIVERSITY;DACOSTA, LUIS;VOGELSTEIN, BERT;KINZLER, KENNETH, W.;HE, TONG-CHUAN
