PLASMID PCDT, METHOD OF PREPARATION AND APPLICATION THEREOF

摘要

biotechnology. SUBSTANCE: invention aims to selectively eliminate cells infected with hepatitis C virus or infection RNA thereof. For that, into cells is introduced plasmid pcDT encoding pseudo hepatitis C virus "-" RNA and capable of orienting synthesis of A subunit of diphtheria toxin in hepatitis C virus-infected cells. Such RNA does not kill sound cells and is incapable of translation. EFFECT: enlarged resource for preparing antihepatitis vaccines. 3 cl, 1 dwg