摘要 |
This invention provides a method of preventing the formation of advanced glycation products through administering a xanthine-based compound, for example, lisofylline. The method is useful in treatments for diseases associated with advanced glycation end-products, such as diabetes, Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Down's syndrome, osteoarthritis, cataracts, cardiac hypertrophy, arterial stiffening, atherosclerosis and kidney toxicity. |