PROCESS FOR THE LARGE-SCALE SYNTHESIS OF 4,10-DINITRO -2,6,8,12- TETRAOXA- 4,10-DIAZATETRACYCLO- [5.5.0.0<5,9>0<3,11>]- DODECANE

摘要

A process for synthesizing 4,10-dinitro-2,6,8,12-tetraoxa-4,10-diazatetracyclo-[5.5.0.0<5,9>0<3,11>]-dodecane ("TEX") involves combining at least one hexa-substituted piperazine derivative with a medium containing at least one nitronium anion source and at least one acid sufficiently strong to generate nitronium anions from the nitronium anion source. According to this invention, TEX yield is significantly improved by pre-heating the medium to 55 DEG C to about 70 DEG C and maintaining the medium from 55 DEG C to about 70 DEG C to permit the hexa-substituted piperazine derivative and nitronium anions to react and form the TEX. At least one NOx scavenger is added to the medium, preferably before the addition of the hexa-substituted piperazine derivative, to increase TEX yield.