发明名称 |
POLYMERS CONTAINING SPIROBICYCLIC AMMONIUM MOIETIES AND USE THEREOF |
摘要 |
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective amount of a spirobicyclic ammonium moiety-containing polymer composition to a mammal, such as a human, whereby bile acids are sequestered. The polymers of the invention comprise spirobicyclic ammonium moieties and optionally, further comprise a hydrophobic substituent, a quaternary ammonium-containing substituent or a combination thereof.
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申请公布号 |
WO0032656(A3) |
申请公布日期 |
2000.11.16 |
申请号 |
WO1999US28139 |
申请日期 |
1999.11.24 |
申请人 |
GELTEX PHARMACEUTICALS, INC. |
发明人 |
DHAL, PRADEEP, K.;POLOMOSCANIK, STEVEN, C. |
分类号 |
A61K31/787;C08F220/04;C08F220/06;(IPC1-7):C08F8/44;A61K31/785;C08F26/06 |
主分类号 |
A61K31/787 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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