发明名称 |
HIGH PURITY (1R,2S,4R)-(-)-2- [(2'-{N,N- DIMETHYLAMINO} -ETHOXY)] -2-[PHENYL] -1,7,7-TRI-[METHYL] -BICYCLO[2.2.1] HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF AND A PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE |
摘要 |
The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N- dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1,7,7-tri- [methyl] -bicyclo [2.2.1] heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.
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申请人 |
EGIS GYOGYSZERGYAR RT.;LUKACS, GYULA;SIMIG, GYULA;MEZEI, TIBOR;BUDAI, ZOLTAN;PORCS-MAKKAY, MARTA;KRASZNAI, GYOERGY;NAGY, KALMAN;VERECZKEYNE DONATH, GYOERGYI;SZABO, TIBOR;NEMETH, NORBERT;SZULAGYI, JANOS |
发明人 |
LUKACS, GYULA;SIMIG, GYULA;MEZEI, TIBOR;BUDAI, ZOLTAN;PORCS-MAKKAY, MARTA;KRASZNAI, GYOERGY;NAGY, KALMAN;VERECZKEYNE DONATH, GYOERGYI;SZABO, TIBOR;NEMETH, NORBERT;SZULAGYI, JANOS |