Novel boronic acid and ester and carboxyl-modified amino acid compounds of the Formula I, which are inhibitors of trypsin-like enzymes, are disclosed:R1-Z-CHR2-A,where R1, Z, R2 and A are defined within.
申请公布号
EP0810858(A4)
申请公布日期
2000.11.15
申请号
EP19950944331
申请日期
1995.12.13
申请人
DUPONT PHARMACEUTICALS COMPANY
发明人
AMPARO, EUGENE CRUZ;MILLER, WILLIAM HENRY;PACOFSKY, GREGORY JAMES;WITYAK, JOHN;WEBER, PATRICIA CAROL;DUNCIA, JOHN JONAS VYTAUTAS;SANTELLA, JOSEPH BASIL, III