发明名称 |
Prostate cancer gene |
摘要 |
<p>The present invention relates to PG1, a gene associated with prostate cancer. The invention provides polynucleotides including biallelic markers derived from PG1 and from flanking genomic regions. Primers hybridizing to these biallelic markers and regions flanking are also provided. This invention provides polynucleotides and methods suitable for genotyping a nucleic acid containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and prostate cancer and between a haplotype and prostate cancer. The invention also relates to diagnostic methods of determining whether an individual is at risk for developing prostate cancer, and whether an individual suffers from prostate cancer as a result of a mutation in the PGl gene.</p> |
申请公布号 |
EP1052292(A1) |
申请公布日期 |
2000.11.15 |
申请号 |
EP20000115991 |
申请日期 |
1998.12.22 |
申请人 |
GENSET |
发明人 |
COHEN, DANIEL;BLUMENFELD, MARTA;CHUMAKOU, ILYA;BOUGUELERET, LYDIE |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|