| 发明名称 |
TRANSGENIC NON-HUMAN ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES |
| 摘要 |
A transgenic mouse having a genome comprising a human immunoglobulin heavy chain minilocus transgene, the transgene being capable of rearrangement and switching in the mouse, whereby two or more rearranged human heavy chain isotypes are produced. |
| 申请公布号 |
KR100272077(B1) |
申请公布日期 |
2000.11.15 |
| 申请号 |
KR19997001717 |
申请日期 |
1999.03.02 |
| 申请人 |
GEN-PHARM INTERNATIONAL,INC. |
发明人 |
LONBERG\, NILS;KAY, ROBERTM. |
| 分类号 |
A01K67/027;A61K38/00;A61K39/395;C07K14/725;C07K16/00;C07K16/18;C07K16/28;C07K16/30;C07K16/42;C07K16/44;C07K16/46;C12N5/10;C12N5/16;C12N15/00;C12N15/09;C12N15/13;C12N15/85;C12N15/87;C12N15/90;C12P21/08;(IPC1-7):C12N15/00 |
主分类号 |
A01K67/027 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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