摘要 |
<p>A heterocyclic halide represented by a general formula (I): T-CH2-Y (wherein T denotes a heterocyclic group, and Y denotes a chlorine atom, bromine atom or iodine atom), is reacted with ammonia in the presence of an aromatic aldehyde represented by a general formula (II): A-CHO (wherein A denotes an aromatic group), to thereby produce an aminomethyl-heterocyclic derivative represented by a general formula (III): T-CH2-N=CH-A (wherein T denotes a heterocyclic group, and A denotes an aromatic group).</p> |