发明名称 Pharmaceutical preparation for inhibiting proliferation of cells of smooth musculature and for inhibiting restenosis
摘要 In the present invention there is disclosed the use of the compound of the general formula I or II, in which Re1 and Re3 represent independently on each other a hydrogen atom, methyl or the group of the general formula -C(=O)-(Ci1-Ci6alkyl) or -C(=O)-Ar, wherein Ar represents a phenyl group, being optionally substituted once or twice with an alkyl group containing 1 to 6 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a hydroxy group, a nitro group, a chlorine atom, a fluorine atom or trichloro- or fluoromethyl group, Re2 is selected from a group of specified heterocyclic groups containing 4 to 6 carbon atoms and 1 nitrogen atom of the general formula (a), (b) and (c), Re4 represents a hydrogen atom or the group of the general formula -ORe1 or pharmaceutically acceptable salt or solvate thereof for preparing a pharmaceutical preparation for inhibiting proliferation of smooth musculature cells and for inhibiting restenosis.
申请公布号 CZ287419(B6) 申请公布日期 2000.11.15
申请号 CZ19940002535 申请日期 1994.10.13
申请人 ELI LILLY AND COMPANY 发明人 CULLINAN GEORGE JOSEPH;SINGH JAI PAL;WOOD DAN LEE
分类号 C07D295/08;A61K31/38;A61K31/381;A61K31/40;A61K31/402;A61K31/4025;A61K31/445;A61K31/4453;A61K31/4535;A61K31/55;A61P9/10;A61P9/14;C07D333/64;(IPC1-7):A61K31/445;A61K31/453 主分类号 C07D295/08
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