发明名称 Remedies for neuropathic pain
摘要 The present invention relates to a compound represented by Formula (I) below: <CHEM> (wherein A represents, for example, phenyl group substituted by R<1> and R<2>, or an unsubstituted furyl group or an unsubstitued thienyl group; R<1> represents, for example, hydrogen atom, fluorine atom, chlorine atom, trifluoromethyl group, nitro group, cyano group or methyl group while R<2> represents, for example, hydrogen atom; R<3> represents, for example, hydrogen atom or methyl group; R<4> represents, for example, hydrogen atom or methyl group; R<5> represents ethoxy group or isopropoxy group; X represents group: -CH(OH)- or methylene group; and Z represents, for example, a single bond or methylene group unsubstituted or substituted by hydroxyl group), and its salts, and medicinal compositions containing, as their active ingredient, the above compound or its salts. The compound of this invention, which is orally applicable, is highly effective for treating neuroapthic pain while presenting with fewer side-effects than do the conventional analgesics.
申请公布号 AU3676100(A) 申请公布日期 2000.11.14
申请号 AU20000036761 申请日期 2000.04.10
申请人 MOCHIDA PHARMACEUTICAL CO., LTD. 发明人 ICHIRO YAMAMOTO;MANABU ITOH;FUMIAKI YAMASAKI;YASUSHIGE AKADA;YUTAKA MIYAZAKI;SHINICHI OGAWA
分类号 A61P25/04;A61P29/02;C07D211/48;C07D405/06;C07D407/06;C07D409/06 主分类号 A61P25/04
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