发明名称 |
Cyclic compounds, their production and use |
摘要 |
Novel compounds of the following general formula or salts thereof. wherein Ring M is a heterocyclic ring having -N=CC<, -CO-N< or -CS-N< as the partial structure -X +E,ovs . . . . .+EE Y<; Ra and Rb are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, and at least one of them is optionally substituted heterocyclic ring; Ring C is optionally substituted homocyclic or heterocyclic ring; Ring Z is an optionally substituted ring; and n represents an integer of from 1 to 6, or a salt thereof, which has an excellent tachykinin receptor antagonistic effect, and their production, and pharmaceutical compositions.
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申请公布号 |
US6147071(A) |
申请公布日期 |
2000.11.14 |
申请号 |
US19980087894 |
申请日期 |
1998.06.01 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
NATSUGARI, HIDEAKI;ISHIMARU, TAKENORI;DOI, TAKAYUKI;IKEURA, YOSHINORI;KIMURA, CHIHARU |
分类号 |
A61P11/06;A61P19/02;C07D471/04;C07D471/14;C07D498/04;(IPC1-7):A61K31/55;A61K31/553;A61K31/554;C07D267/22;C07D267/02 |
主分类号 |
A61P11/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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