发明名称 Cyclic compounds, their production and use
摘要 Novel compounds of the following general formula or salts thereof. wherein Ring M is a heterocyclic ring having -N=CC<, -CO-N< or -CS-N< as the partial structure -X +E,ovs . . . . .+EE Y<; Ra and Rb are bonded to each other to form Ring A, or they are the same or different and represent, independently, a hydrogen atom or a substituent on the Ring M; Ring A and Ring B represent, independently, an optionally substituted homocyclic or heterocyclic ring, and at least one of them is optionally substituted heterocyclic ring; Ring C is optionally substituted homocyclic or heterocyclic ring; Ring Z is an optionally substituted ring; and n represents an integer of from 1 to 6, or a salt thereof, which has an excellent tachykinin receptor antagonistic effect, and their production, and pharmaceutical compositions.
申请公布号 US6147071(A) 申请公布日期 2000.11.14
申请号 US19980087894 申请日期 1998.06.01
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 NATSUGARI, HIDEAKI;ISHIMARU, TAKENORI;DOI, TAKAYUKI;IKEURA, YOSHINORI;KIMURA, CHIHARU
分类号 A61P11/06;A61P19/02;C07D471/04;C07D471/14;C07D498/04;(IPC1-7):A61K31/55;A61K31/553;A61K31/554;C07D267/22;C07D267/02 主分类号 A61P11/06
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