| 摘要 |
The present invention describes a polyoxaester copolymer and blends thereof that may be used to produce hydrogels, surgical devices such as sutures, sutures with attached needles, molded devices, drug matrices, adhesives, sealants and the like. The invention also contemplates a process for producing these polyesters. The polyoxaester copolymers of the present invention are formed from a first divalent repeating unit of formula IA:[-O-C(O)-R30-C(O)-]IAa second divalent repeating unit of the formula IB:[O-C(O)-C(R1)(R2)-O-R3-O-C(R'1)(R'2)-C(O)-]IBand a third repeating unit selected from the group of formulas consisting of:[-O-R4-]A,II[-O-R5-C(O)-]B,III([-O-R5-C(O)]P-O-)LGXIand combinations thereof. These aliphatic polyoxaesters may be blended with other polymers that are preferably biocompatable.
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