发明名称 Imidazole derivatives as anti-HIV agents
摘要 An imidazole derivative represented by general formula (I) or a salt thereof, having the effect of specifically inhibiting the growth of HIV as a pathogenic virus and being reduced in toxicity. In said formula R1 represents hydrogen, C1-C20 alkyl, C2-C7) alkenyl, C4-C12 cycloalkylalkyl, etc.; R2 represents C1-C6 alkyl, C1-C6 acyl, hydroxyiminomethyl, hydrazonomethyl or -(CH2)n-R4 (R4 being halogeno, alkoxy, hydroxy, etc.; and n being an integer of 1 to 3); R3 represents substituted or unsubstituted C1-C6 alkyl; X and Y represent each independently hydrogen, C1-C3 alkyl, halogeno, or nitro; and Z represents S, SO, SO2 or CH2.
申请公布号 US6147097(A) 申请公布日期 2000.11.14
申请号 US19980205289 申请日期 1998.12.04
申请人 SHIONOGI & CO., LTD. 发明人 SUGIMOTO, HIROHIKO;FUJIWARA, TAMIO
分类号 A61K31/4164;A61K31/4178;A61P31/18;C07D233/54;C07D233/58;C07D233/60;C07D233/64;C07D233/84;C07D401/04;C07D401/06;C07D409/04;(IPC1-7):A61K31/416;A61K31/441 主分类号 A61K31/4164
代理机构 代理人
主权项
地址