METHOD FOR ASSESSING THE RISK OF PEPTIC ULCER, COMPRISING THE STEPS OF DETERMINING QUANTITATIVELY THE CONCENTRATIONS OF PEPSINOGEN I (PGI) AND GASTRIN-17 IN A SERUM SAMPLE

摘要

The present invention concerns a method for assessing the risk of peptic ulcer by determining the presence and topographic phenotype of gastritis in an individual, by determining quantitatively the pepsinogen I and gastrin-17 concentrations in a serum sample from the said individual, selecting a method-specific reference value and cut-off value for respective analyte, assessing the topography and phenotype of gastritis based on a comparison of the pepsinogen I and gastrin-17 concentrations so determined with their respective method-specific reference and cut-off values, and correlating the so assessed gastritis phenotype with the risk for peptic ulcer. Preferably also Helicobacter antibodies are determined in the sample.