发明名称 |
ANTI-INFLAMMATORY BIOACTIVE GLASS PARTICULATES |
摘要 |
Compositions and methods for systemically minimizing the inflammatory effect s of TNF-.alpha. are disclosed. The compositions include particles of bioactiv e glass with a particle size less than about 20 .mu.m, alone or in combination with anti-inflammatory agents and other therapeutic agents. The compositions can include an appropriate carrier for oral, intramuscular, intraperitoneal or intravenous administration. When administered to a patient, the particles bring about elevated levels of IL-6 and do not cause elevated levels of TNF- .alpha.. |
申请公布号 |
CA2372384(A1) |
申请公布日期 |
2000.11.09 |
申请号 |
CA20002372384 |
申请日期 |
2000.04.28 |
申请人 |
USBIOMATERIALS CORPORATION |
发明人 |
LEE, SEAN;WALPOLE, MARLO TAN;GREENSPAN, DAVID C. |
分类号 |
A61K45/00;A61K9/16;A61K33/00;A61K33/08;A61K33/42;A61K45/06;A61K47/04;A61P1/16;A61P1/18;A61P3/12;A61P3/14;A61P9/00;A61P9/10;A61P11/00;A61P17/02;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P37/06;A61P41/00;A61P43/00;C03C3/097;C03C4/00;C03C12/00;(IPC1-7):A61K9/14 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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