| 发明名称 |
1-AMINO TRIAZOLO CENT 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV |
| 摘要 |
The invention relates to triazolo[4,3-a]quinazoline-5-ones and/or 5-thiones of formula (I) or (II), whereby (I) and (II) are position isomers of group R on nitrogen 3 or 4. Optionally, the invention also relates to the racemic forms, isomers and pharmaceutically acceptable salts thereof. The invention further relates to a method for the production thereof and to compositions containing said derivatives. The compounds act as inhibitors of phosphodiesterase IV (PDE-4).
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| 申请公布号 |
WO0066584(A1) |
申请公布日期 |
2000.11.09 |
| 申请号 |
WO2000FR01174 |
申请日期 |
2000.04.28 |
| 申请人 |
WARNER-LAMBERT COMPANY;GAUDILLIERE, BERNARD;LAVALETTE, REMI;ANDRIANJARA, CHARLES;BREUZARD, FRANCINE |
发明人 |
GAUDILLIERE, BERNARD;LAVALETTE, REMI;ANDRIANJARA, CHARLES;BREUZARD, FRANCINE |
| 分类号 |
A61K;A61K31/4985;A61K31/505;A61K31/519;A61K31/5377;A61K31/541;A61K31/55;A61P1/00;A61P1/18;A61P3/10;A61P9/00;A61P9/04;A61P9/12;A61P11/00;A61P11/06;A61P13/08;A61P15/06;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/24;A61P25/28;A61P25/36;A61P35/00;A61P43/00;C07D;C07D239/22;C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
A61K |
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