发明名称 |
Modified factor VIII cDNA |
摘要 |
A modified Factor VIII cDNA is described in which the B-domain of the wild-type Factor VIII cDNA has been deleted and a truncated Factor IX intron 1 has been inserted in one or more locatons of the Factor VIII cDNA. Such modified Factor VIII cDNA may be used for a higher yield production of Factor VIII in vitro as well as in a transfervector for gene therapy. |
申请公布号 |
AU2231200(A) |
申请公布日期 |
2000.11.09 |
申请号 |
AU20000022312 |
申请日期 |
2000.03.15 |
申请人 |
AVENTIS BEHRING GMBH |
发明人 |
CLAUDE NEGRIER;JEAN LUC PLANTIER |
分类号 |
C12N15/09;A61K48/00;A61P7/04;C07K14/755;C12N5/10;C12N15/12;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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