发明名称 |
PROTEIN SPECIFIC FOR CARDIAC AND SKELETAL MUSCLE |
摘要 |
The present invention relates to a muscle-specific protein, Ozz, and nucleic acids encoding the protein, that regulates development and function of muscle cells. The invention further relates to muscle-specific regulated expression of the protein, and of heterologous genes under control of the same regulatory sequences. In a specific example, a murine Ozz protein of 285 amino acids is preferentially expressed by a 1.0 kb mRNA in heart and skeletal muscle. This protein shares significant homology with neuralized proteins, and associates with a number of muscle proteins, including beta -catenin.
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申请公布号 |
WO0066733(A1) |
申请公布日期 |
2000.11.09 |
申请号 |
WO2000US11900 |
申请日期 |
2000.04.28 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL;D'AZZO, ALESSANDRA;BONGIOVANNI, ANTONELLA;NASTASI, TOMMASO |
发明人 |
D'AZZO, ALESSANDRA;BONGIOVANNI, ANTONELLA;NASTASI, TOMMASO |
分类号 |
C07K14/47;C12N15/12;(IPC1-7):C12N15/12;C12Q1/68;C07K16/18;A01K67/027;G01N33/577 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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