| 发明名称 |
GLUCOCORTICOID RECEPTOR MODULATORS |
| 摘要 |
The present invention provides non-steroidal compounds of formula (I) which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators a re useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides intermediates and processes for preparing these compounds.
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| 申请公布号 |
CA2372173(A1) |
申请公布日期 |
2000.11.09 |
| 申请号 |
CA20002372173 |
申请日期 |
2000.03.27 |
| 申请人 |
PFIZER PRODUCTS INC., |
发明人 |
DOW, ROBERT LEE;SWICK, ANDREW GORDON;MORGAN, BRADLEY PAUL;LIU, KEVIN KUN-CHIN |
| 分类号 |
C07D295/12;A61K31/05;A61K31/122;A61K31/27;A61K31/275;A61K31/325;A61K31/40;A61K31/4164;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4965;A61K31/5375;A61P3/04;A61P3/10;A61P11/06;A61P19/02;A61P25/22;A61P25/24;A61P25/28;A61P27/16;A61P29/00;A61P37/02;A61P43/00;C07C35/42;C07C49/675;C07C49/737;C07C49/747;C07C49/755;C07C49/757;C07C65/17;C07C69/00;C07C215/50;C07C215/74;C07C225/22;C07C233/58;C07C235/48;C07C235/66;C07C247/24;C07C251/44;C07C251/52;C07C251/60;C07C255/53;C07C255/54;C07C271/10;C07C271/44;C07C271/52;C07C281/04;C07C307/02;C07C309/65;C07C309/66;C07C309/73;C07C311/04;C07C311/08;C07C311/51;C07C317/18;C07C333/04;C07D207/09;C07D211/46;C07D213/22;C07D213/30;C07D213/40;C07D213/75;C07D231/40;C07D231/56;C07D233/61;C07D239/34;C07D241/12;C07D241/18;C07D241/20;C07D249/08;C07D249/14;C07D257/04;C07D271/06;C07D271/07;C07D277/24;C07D277/28;C07D277/56;C07D295/092;C07D295/13;C07D295/185;C07D295/205;C07D303/14;C07D317/36;C07D333/16;C07D413/04;C07D455/06;(IPC1-7):C07C35/42;A61K31/440 |
主分类号 |
C07D295/12 |
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