Methods of diagnosing or treating neuropsychiatric diseases on basis of increased cerebrospinal fluid levels of neurotrophin 3

摘要

The invention relates to a method for diagnosing or prognosing a neurodegenerative or neuropsychiatric disease in a subject, or determining whether a subject is at increased risk of developing a neurodegenerative or neuropsychiatric disease, comprising: determining a level of neurotrophin 3 and/or of a transcription product of a gene coding for neurotrophin 3 in a sample from said subject; and comparing said level to a reference value representing a known disease or health status, thereby diagnosing or prognosing said neurodegenerative or neuropsychiatric disease in said subject, or determining whether said subject is at increased risk of developing a neurodegenerative or neuropsychiatric disease.