发明名称 A METHOD OF PREPARING A FIBRINOGEN CONCENTRATE FROM BLOOD PLASMA, A DEVICE FOR CARRYING OUT SAID METHOD, AND A METHOD OF PREPARING FIBRINOGEN FROM SAID CONCENTRATE
摘要 A method of preparing fibrinogen concentrate from blood plasma by cooling said plasma from a temperature above 0 .degree.C to a first temperature between -10 .degree.C and -40 .degree.C, thawing the solid material thus obtained to a temperature near the freezing point of water and subsequently physically separating the solid matter and the liquid main fraction of the plasma, viz, water, whereby the thawing is effected in steps from the first temperature to a conditioning temperature between -5 .degree.C and -1 .degree.C, after which the size of the solid material is reduced and the reduced material is brought to a temperature at which the main fraction of the plasma, viz, water, becomes liquid and the solubility of fibrinogen in said fluid is as low as possible, after which fluid is separated from the fibrinogen concentrate. The invention also relates to a device for carrying out this method.
申请公布号 CA2034100(C) 申请公布日期 2000.11.07
申请号 CA19912034100 申请日期 1991.01.14
申请人 发明人 VAN DOMMELEN, FREDERIK SUSAN;WIJNGAARDS, GERRIT
分类号 A61K35/14;A23J1/06;A61K35/16;A61K38/00;A61M1/34;A61M1/36;C07K14/75;(IPC1-7):C07K14/75;C07K1/36 主分类号 A61K35/14
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