发明名称 Aminothiophene carboxylic acid amides and the use thereof as phosphodiesterase inhibitors
摘要 PCT No. PCT/EP97/05531 Sec. 371 Date Apr. 14, 1999 Sec. 102(e) Date Apr. 14, 1999 PCT Filed Oct. 8, 1997 PCT Pub. No. WO98/16521 PCT Pub. Date Apr. 23, 1998Aminothiophenecarboxamides of the formula I and their physiologically acceptable salts, wherein R1, R2, R3, R4, R5, A and n have the meanings stated in claim 1, exhibit phosphodiesterase V inhibition and can be used for the treatment of diseases of the cardiovascular system and for the therapy of disturbances of potency.
申请公布号 US6143777(A) 申请公布日期 2000.11.07
申请号 US19990284501 申请日期 1999.04.14
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 JONAS, ROCHUS;SCHELLING, PIERRE;KLUXEN, FRANZ-WERNER;CHRISTADLER, MARIA
分类号 A61K31/38;A61K31/381;A61P9/00;A61P15/10;A61P43/00;C07D333/38;C07D333/68;C07D333/70;C07D333/78;C07D333/80;C07D409/12;(IPC1-7):A61K31/38;C07D333/56;C07D407/00;C07D333/36 主分类号 A61K31/38
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