发明名称 |
pH-modified biocompatible monomer and polymer compositions |
摘要 |
The pH-modified monomer and polymer compositions are useful as biomedical and surgical adhesives, sealants, implants and bioactive agent release carriers or matrices. They comprise a monomer or polymer; and an effective amount of an acidic or basic pH modifier effective to modify the pH of an immediate in vivo environment of the composition to a pH range at which the polymer biodegrades at a different rate than at physiologic pH. The invention also relates to in vivo applications in which surfaces are joined or treated with such pH-modified biocompatible compositions.
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申请公布号 |
US6143352(A) |
申请公布日期 |
2000.11.07 |
申请号 |
US19960714288 |
申请日期 |
1996.09.18 |
申请人 |
CLOSURE MEDICAL CORPORATION |
发明人 |
CLARK, JEFFREY G.;LEUNG, JEFFREY C. |
分类号 |
A61K47/30;A61L24/00;A61L24/04;A61L24/06;A61L27/00;A61L27/16;A61L27/26;C08F2/00;C09J4/00;C09J4/04;(IPC1-7):B05D3/00 |
主分类号 |
A61K47/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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