发明名称 |
IDENTIFICATION OF LIGANDS FOR ORPHAN RECEPTORS USING MASS SPECTROMETRY |
摘要 |
The present invention relates to the on-line coupling of mass spectrometry (MS) to continuous-flow separation techniques for detecting orphan analytes, viz. receptors which do not have known ligands. In a further embodiment, this on-line detection method is used as either a screening method for assays with an unknown ligand. Furthermore, this invention relates to compounds detected by this method and the use of these compounds as a ligand for affinity molecules.
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申请公布号 |
WO0065353(A1) |
申请公布日期 |
2000.11.02 |
申请号 |
WO2000NL00268 |
申请日期 |
2000.04.26 |
申请人 |
SCREEN TEC B.V.;VAN DER GREEF, JAN;IRTH, HUBERTUS |
发明人 |
VAN DER GREEF, JAN;IRTH, HUBERTUS |
分类号 |
G01N27/62;B01D63/02;G01N27/447;G01N30/02;G01N30/46;G01N30/72;G01N30/84;G01N30/88;G01N33/493;G01N33/538;G01N33/566;(IPC1-7):G01N33/566 |
主分类号 |
G01N27/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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