发明名称 |
LIGANDS FOR METABOTROPIC GLUTAMATE RECEPTORS |
摘要 |
The present invention relates to novel compounds and formulations thereof which compounds are ligands, e.g., agonists or antagonists, for a metabotropic glutamate receptor or a NAALADase enzyme or both. The present invention also relates to methods of modulating the activity of a metabotropic glutamate receptor or a NAALADase enzyme or both, e.g., in a subject in need thereof, using a compound or formulation of the present invention. The present invention also relates to methods of treating a subject suffering from a chronic or acute disease, malady or condition due at least in part to an abnormality in the activity of an endogenous metabotropic glutamate receptor or a NAALADase enzyme or both, using a compound or formulation of the present invention.
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申请公布号 |
WO0064911(A1) |
申请公布日期 |
2000.11.02 |
申请号 |
WO2000US11262 |
申请日期 |
2000.04.27 |
申请人 |
GEORGETOWN UNIVERSITY |
发明人 |
KOZIKOWSKI, ALAN, P.;WROBLEWSKI, JARDA, T.;NAN, FAJUN |
分类号 |
A61K31/662;A61K31/194;A61K31/197;A61K31/198;A61K31/22;A61K31/225;A61P3/00;A61P9/00;A61P9/10;A61P25/00;A61P25/02;A61P25/08;A61P25/16;A61P25/28;A61P31/04;A61P39/00;A61P41/00;A61P43/00;C07C59/347;C07C69/716;C07C275/16;C07C335/08;C07F9/30;C07F9/32;(IPC1-7):C07F9/30;C07C273/16 |
主分类号 |
A61K31/662 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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