发明名称 |
Modified factor VIII cDNA |
摘要 |
A modified Factor VIII cDNA is described in which the B-domain of the wild-type Factor VIII cDNA has been deleted and a truncated Factor IX intron 1 has been inserted in one or more locatons of the Factor VIII cDNA. Such modified Factor VIII cDNA may be used for a higher yield production of Factor VIII in vitro as well as in a transfervector for gene therapy. <IMAGE>
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申请公布号 |
EP1048726(A2) |
申请公布日期 |
2000.11.02 |
申请号 |
EP20000104677 |
申请日期 |
2000.03.03 |
申请人 |
CENTEON PHARMA GMBH |
发明人 |
NEGRIER, CLAUDE, DR.;PLANTIER, JEAN LUC |
分类号 |
C07K14/755;C12N15/12;C12N15/67;(IPC1-7):C12N15/12 |
主分类号 |
C07K14/755 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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