发明名称 |
Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
摘要 |
Compounds of formula I are disclosed. as well as pharmaceutically acceptable salts thereof. The naphthosultam is substituted with various substituent groups including at least one cationic group -A-Q-L-B. The carbapenems of the invention are effective against susceptible bacterial organisms, including methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and methicillin resistant coagulase negative Staphylococci (MRCNS).
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申请公布号 |
US6140318(A) |
申请公布日期 |
2000.10.31 |
申请号 |
US19980168622 |
申请日期 |
1998.10.08 |
申请人 |
MERCK & CO., INC. |
发明人 |
CAMA, LOVJI D.;WILKENING, ROBERT R.;RATCLIFFE, RONALD W.;WILDONGER, KENNETH J.;SUN, WANYING |
分类号 |
A61P31/06;C07D487/04;(IPC1-7):A61K31/395;A01N43/60;C07D487/00;C07D413/00 |
主分类号 |
A61P31/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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