| 发明名称 |
Proteins with mutations to decrease N-terminal methylation |
| 摘要 |
This invention relates to proteins with N-terminal modifications in their amino acid sequence that reduce or eliminate the methylation of the N-terminal methionine that occurs when such proteins are produced in bacteria such as E. coli.
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| 申请公布号 |
US6140071(A) |
申请公布日期 |
2000.10.31 |
| 申请号 |
US19940188374 |
申请日期 |
1994.01.27 |
| 申请人 |
SOMATOGEN, INC. |
发明人 |
AITKEN, JACQUELINE F.;APOSTOL, IZYDOR Z.;LIPPINCOTT, JULIE A.;LEVINE, JOSEPH D. |
| 分类号 |
A61K38/00;C07K14/805;C12N15/10;(IPC1-7):C12P21/06;C12N1/20;C12N15/00;C07K1/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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